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MTN-035/DESIRE (Developing and Evaluating Short-acting Innovations for Rectal Use) – An acceptability, tolerability and adherence study of three placebo products for use in the rectum, including a douche, suppository and fast-dissolving rectal insert. The goal of the study is to help answer important questions about preferences for future rectal microbicide products. The products, which contain no active drugs, are being evaluated in 217 HIV-negative cisgender men, transgender men and transgender women who have sex with men at sites in Malawi, Peru, South Africa, Thailand and the U.S.  Final results are expected by mid-2021.

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06-March-2021

What Do People Who Practice Anal Sex Desire for Preventing HIV?
10-April-2019

MTN-035 Backgrounder

MTN-035 Q&A

See Also
MTN-035 Protocol

MTN-035 Study Page